omega-Conotoxin MVIIA (omega conotoxin MVIIA)

N° du produit ABIN1540040

Aperçu rapide pour omega-Conotoxin MVIIA (omega conotoxin MVIIA) (ABIN1540040)

Antigène: omega-Conotoxin MVIIA

Application: Blocking Reagent (BR)

Détail du produit

Fonction: omega-Conotoxin MVIIA is a Cav2.2 channel blocker

Séquence: Cys1-Lys-Gly-Lys-Gly-Ala-Lys-Cys8-Ser-Arg-Leu-Met-Tyr-Asp-Cys15-Cys16-Thr-Gly-Ser-Cys20-Arg-Ser-Gly-Lys-Cys25-NH2Disulfide bonds between Cys1-Cys16, Cys8-Cys20and Cys15-Cys25

Information d'application

Restrictions: For Research Use only

Stockage

Détail du antigène

Antigène: omega-Conotoxin MVIIA

Sujet: Omega-Conotoxin MVIIA has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC). This toxin blocks N-type calcium channels (Cav2.2/CACNA1B). Omega-conotoxin MVIIA is available under the name Prialt by Neurex. It blocks acute pain in patients who no longer obtain relief from opiate drugs. It is 100 to 1.000 times more potent than morphine. This toxin blocks calcium channels and disables nerves that transmit pain signals.

Poids moléculaire: 2639.18 Da

Numéro CAS: 107452-89-1